How does salmonella typhi cause disease?
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Bacteriology
6 years
2018-11-22T07:42:27+00:00
2018-11-22T07:42:27+00:00 1 Answer
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Answer ( 1 )
salmonella typhi causes disease by the ingestion of that strain through the contaminated food or water. salmonella typhi causes typhoid fever and it’s more prevalent than Salmonella paratyphi
Mechanism:
salmonella enters through the ingestion and then attach to the microvilli, ileal mucosa, penetrate to lamina propria and submucosa. salmonella typhi multiplies within the phagocytic cell. intracellular multiplication continues in the cell of the reticuloendothelial system and then done the hypoplastic changes in the lymphoid tissue and due to this done the necrosis, haemorrhages, perforation of the intestinal wall and after that enter the bloodstream through the thoracic duct and cause the infection of gall bladder also.
hope you got it.
thanks