Answer ( 1 )

  1. Yes, Escherichia coli (E. coli) is oxidase negative. This means that it lacks the enzyme oxidase, which is used in the oxidase test to detect the presence of cytochrome c oxidase in certain bacteria. When a sample is treated with an oxidase reagent, bacteria that possess cytochrome c oxidase will produce a color change, indicating a positive result. However, E. coli and other members of the Enterobacteriaceae family are oxidase negative, meaning they do not produce a color change in the oxidase test. This characteristic is useful in differentiating E. coli from other bacteria in the laboratory.

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