Dna binding proteins


How experimentally would you detemine a protein is dna binding ?

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Sam4545 2020-08-19T21:32:15+00:00 1 Answer 181 views New Member 0

Answer ( 1 )


    different forces is involves while interacting DNA with the protein i.e. hydrogen bond, dipolar interaction etc. .. you can perform different experiments to find the DNA -protein interaction and the following method is:

    • Down pull down assay
    • micro plate capture and  detection assay
    • DNA electrophoretic mobility shift assay
    • chromatin immuoprecipitation assay

    These experiments helps u to find our your answer..

    also i would prefer you to read this article for further information .. it will definitely help you out


    hope you got the point


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