Answer ( 1 )


    salmonella typhi causes the only disease in humans and can transfer by the ingestion of that strain through the contaminated food or water and faecal-oral route is also the major cause of the transfer of this infection. salmonella typhi causes typhoid fever and it’s more prevalent than Salmonella paratyphi


    salmonella enters through the ingestion and then attach to the microvilli, ileal mucosa, penetrate to lamina propria and submucosa. salmonella typhi multiplies within the phagocytic cell. salmonella typhi has Vi capsular antigen that helps to avoid the neutrophil based inflammation as well. intracellular multiplication continues in the cell of the reticuloendothelial system and then done the hypoplastic changes in the lymphoid tissue and due to this done the necrosis, haemorrhages, perforation of the intestinal wall and after that enter the bloodstream through the thoracic duct and cause the infection of gall bladder also. S.typhi continue to multiply until it reaches the critical density i.e. 1,000,000 in order to cause the infection.

    hope you got it.


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