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    Salmonella is the chief causative agent of a severe disease typhoid and also cause many other diseases. Infection caused by salmonella is called salmonellosis.


    Salmonella is a gram-negative rod-shaped bacteria. They are facultative anaerobes that can survive in the absence of oxygen. They are motile and non-spore forming. They are present in the human gut and excrete through feces. Sewage contamination in food leads to the contamination of foods. The sewage contaminations are due to pipe leakage and mixing of sewage water with the food.


    Salmonella doesn’t produce any toxins. Bacteria are present in the food that goes into the intestine by crossing the stomach. In intestine, it adheres to enterocyte and invades in the cell. Salmonella is intracellular pathogen that increases the adenylate cyclase activity. This increases the cAMP level of the intestine that leads to diarrhea. The inflammation of intestine starts when cell lysis occurs. This inflammation is called gastroenteritis.

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